On the Microassembly Integral Membrane Proteins

CONTENTS PERSPECTIVES AND OVERVIEW ........................................................................................ 370 PROCEDURES ................................................................................................................. 371 Hydvophobicity Anctlysis ........................................................................................... 371 Choice ofProteins .................................................................................................... 373 RF~SULTS ........................................................................................................................ 374 ldent~J~ying Putative Transmembrane Se,qments and Estimatin.q Their Hydrophobicity 374 Number and IIydrophobicity of Putative Transmembrane ~-Helices as a Function of Protein Localization a d Function ............................................................... 382 Number and Hydrophobicity of Transmembrane Segments in Organelle InnerMembrane Proteins Dependiny on Site of Synlt~esis ..................................... 383 o~scuss~o~ ................................................................................................................... 387 The Microassembly of Integral Membrane Proteins in Or, qanelles ............................ 387 Other Membranes ..................................................................................................... 395 Displacing the Synthexix of Integral Membrane Proteins from Organelles to the Cytoplasm ................................................................................................... 397 CONCLUSXON ................................................................................................................. 399